American Melody, Upper Mississippi River Cruise ex St. Louis to Red Wing

Journey

7 Night Cruise sailing from Alton to Red Wing onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

Ship

American Melody (More about the ship)

Departure Date

12 Sep 2025

Compare

Itinerary
Cruise Itinerary
- - Day
  - Date
  - Port
  - Arrive
  - Depart
- - Day:Day 1
  - Date:12 Sep 25
  - Port:St Louis, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 1
  - Date:12 Sep 25
  - Port:St Louis, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 1
  - Date:12 Sep 25
  - Port:Alton, Illinois, USA
  - Arrive:
  - Depart:
- - Day:Day 1
  - Date:12 Sep 25
  - Port:St Louis, Missouri, USA
  - Arrive:
  - Depart:Hotel
- - Day:Day 2
  - Date:13 Sep 25
  - Port:Alton, Illinois, USA
  - Arrive:Embark
  - Depart:
- - Day:Day 2
  - Date:13 Sep 25
  - Port:Hannibal, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 2
  - Date:13 Sep 25
  - Port:Hannibal, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 3
  - Date:14 Sep 25
  - Port:Fort Madison, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 3
  - Date:14 Sep 25
  - Port:Fort Madison, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 3
  - Date:14 Sep 25
  - Port:Hannibal, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 4
  - Date:15 Sep 25
  - Port:Fort Madison, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 4
  - Date:15 Sep 25
  - Port:Davenport, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 4
  - Date:15 Sep 25
  - Port:Davenport, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 5
  - Date:16 Sep 25
  - Port:Dubuque, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 5
  - Date:16 Sep 25
  - Port:Dubuque, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 5
  - Date:16 Sep 25
  - Port:Davenport, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 6
  - Date:17 Sep 25
  - Port:Dubuque, Iowa, USA
  - Arrive:
  - Depart:
- - Day:Day 6
  - Date:17 Sep 25
  - Port:Winona, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 6
  - Date:17 Sep 25
  - Port:Winona, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 7
  - Date:18 Sep 25
  - Port:Red Wing, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 7
  - Date:18 Sep 25
  - Port:Red Wing, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 7
  - Date:18 Sep 25
  - Port:Winona, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 8
  - Date:19 Sep 25
  - Port:Red Wing, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 8
  - Date:19 Sep 25
  - Port:St Paul, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 8
  - Date:19 Sep 25
  - Port:Red Wing, Minnesota, USA
  - Arrive:
  - Depart:
- - Day:Day 9
  - Date:20 Sep 25
  - Port:Red Wing, Minnesota, USA
  - Arrive:Disembark
  - Depart:
- - Day:Day 9
  - Date:20 Sep 25
  - Port:St Paul, Minnesota, USA
  - Arrive:Disembark
  - Depart:
** Itinerary may vary by sailing date
Your cruise in detail

7 Night Cruise sailing from Alton to Red Wing onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

Cruise Overview:

A journey along the Upper Mississippi River is an enriching experience, embodying hometown Americana and the breathtaking scenery that has inspired the country’s most legendary writers, artists, and musicians. It was here that the great American writer Mark Twain used the majestic river and its scenic bluffs as the settings in his most popular works. In his book “Life on the Mississippi,” he described traveling on this part of the river as “always through enchanting scenery, there being no other kind on the Upper Mississippi.” Visit his boyhood home in Hannibal, where the characters of Huck Finn, Tom Sawyer, and Becky Thatcher come to life.

Explore the beautiful gardens and historic homes of the region in the company of our carefully selected expert guides. From your private balcony, admire stretches of undeveloped countryside, ornamented with pelicans, soaring eagles, and blue herons. Weave among hundreds of picturesque islands and through the amazing engineering of dams and navigation locks.

Along the way, be treated to the gracious hospitality of our crew and savor an exquisite menu, featuring dishes masterfully prepared by our culinary team, with a dash of local flavor.

NOTE: Just as it was back in Mark Twain’s day, every riverboat on the Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary. The river has a mind of its own and our sailing schedules must adapt to it. This is part of the adventure and American Cruise Lines will always work to provide a seamless travel experience.
Travel dates
- - Departing
  - From
  - Price From
- - Departing:18 Jul 25
  - From:St Louis, Missouri, USA
  - Price from: Ask
  - Details
- - Departing:29 Aug 25
  - From:St Louis, Missouri, USA
  - Price from: Ask
  - Details
- - Departing:12 Sep 25
  - From:St Louis, Missouri, USA
  - Price from: Ask
- - Departing:26 Sep 25
  - From:St Louis, Missouri, USA
  - Price from: Ask
  - Details
- - Departing:10 Oct 25
  - From:St Louis, Missouri, USA
  - Price from: Ask
  - Details

*Terms and Conditions

Information on this website has been obtained from the various Cruise Companies represented, however as the cruise industry is constantly changing and this information should be used as a guide only. We are unable to take responsibility for incorrect information and you must confirm all details the time of booking. Offer subject to availability at time of booking. Prices are per person share twin based on best available cruise fare, inclusive of all discounts unless otherwise stated. Where suite pricing is indicated this will be for lead in suite accommodation only and may in some cases be for a mini suite, which is the lead in suite category. Please ask for clarification at time of enquiry. Prices are subject to currency fluctuations and are based on cash or cheque. Cruise deposit, amendment and cancellation conditions apply. Travel agent service fees may apply. Special conditions apply - please ask for full details at time of enquiry.