American Melody, Grand Ohio River Cruise ex Pittsburgh to St Louis

Journey

14 Night Cruise sailing from Pittsburgh to St Louis onboard American Melody. Complimentary hotel stay pre-cruise in Pittsburgh.

Ship

American Melody (More about the ship)

Departure Date

4 Jul 2025

Compare

Itinerary
Cruise Itinerary
- - Day
  - Date
  - Port
  - Arrive
  - Depart
- - Day:Day 1
  - Date:4 Jul 25
  - Port:Pittsburgh, Pennsylvania, USA
  - Arrive:
  - Depart:Hotel
- - Day:Day 1
  - Date:4 Jul 25
  - Port:Pittsburgh, Pennsylvania, USA
  - Arrive:
  - Depart:
- - Day:Day 2
  - Date:5 Jul 25
  - Port:River Cruising
  - Arrive:
  - Depart:
- - Day:Day 2
  - Date:5 Jul 25
  - Port:Pittsburgh, Pennsylvania, USA
  - Arrive:Embark
  - Depart:
- - Day:Day 3
  - Date:6 Jul 25
  - Port:River Cruising
  - Arrive:
  - Depart:
- - Day:Day 3
  - Date:6 Jul 25
  - Port:Marietta, Ohio, USA
  - Arrive:
  - Depart:
- - Day:Day 4
  - Date:7 Jul 25
  - Port:Maysville, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 4
  - Date:7 Jul 25
  - Port:Marietta, Ohio, USA
  - Arrive:
  - Depart:
- - Day:Day 5
  - Date:8 Jul 25
  - Port:Maysville, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 5
  - Date:8 Jul 25
  - Port:Cincinnati, Ohio, USA
  - Arrive:
  - Depart:
- - Day:Day 6
  - Date:9 Jul 25
  - Port:Cincinnati, Ohio, USA
  - Arrive:
  - Depart:
- - Day:Day 6
  - Date:9 Jul 25
  - Port:Cincinnati, Ohio, USA
  - Arrive:
  - Depart:
- - Day:Day 7
  - Date:10 Jul 25
  - Port:Cincinnati, Ohio, USA
  - Arrive:
  - Depart:
- - Day:Day 7
  - Date:10 Jul 25
  - Port:Louisville, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 8
  - Date:11 Jul 25
  - Port:Louisville, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 8
  - Date:11 Jul 25
  - Port:Louisville, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 9
  - Date:12 Jul 25
  - Port:Louisville, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 9
  - Date:12 Jul 25
  - Port:Henderson, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 10
  - Date:13 Jul 25
  - Port:Evansville, IN, USA
  - Arrive:
  - Depart:
- - Day:Day 10
  - Date:13 Jul 25
  - Port:Henderson, Kentucky, USA
  - Arrive:
  - Depart:
- - Day:Day 11
  - Date:14 Jul 25
  - Port:Evansville, IN, USA
  - Arrive:
  - Depart:
- - Day:Day 11
  - Date:14 Jul 25
  - Port:Paducah, Kentucky,USA
  - Arrive:
  - Depart:
- - Day:Day 12
  - Date:15 Jul 25
  - Port:River Cruising
  - Arrive:
  - Depart:
- - Day:Day 12
  - Date:15 Jul 25
  - Port:Paducah, Kentucky,USA
  - Arrive:
  - Depart:
- - Day:Day 13
  - Date:16 Jul 25
  - Port:River Cruising
  - Arrive:
  - Depart:
- - Day:Day 13
  - Date:16 Jul 25
  - Port:Cape Girardeau, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 14
  - Date:17 Jul 25
  - Port:St Louis, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 14
  - Date:17 Jul 25
  - Port:Cape Girardeau, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 15
  - Date:18 Jul 25
  - Port:St Louis, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 15
  - Date:18 Jul 25
  - Port:St Louis, Missouri, USA
  - Arrive:
  - Depart:
- - Day:Day 16
  - Date:19 Jul 25
  - Port:St Louis, Missouri, USA
  - Arrive:Disembark
  - Depart:
** Itinerary may vary by sailing date
Your cruise in detail

14 Night Cruise sailing from Pittsburgh to St Louis onboard American Melody. Complimentary hotel stay pre-cruise in Pittsburgh.

Cruise Overview:

Experience two of America’s greatest rivers on this enchanting cruise through the Heartland. Immerse yourself in a new element of Americana at each port visited, from the small towns of Kentucky and Ohio to the vibrant metropolis of “Steel City” Pittsburg and St. Louis, the Gateway to the West. As you cruise the Ohio River in the comfort of our new riverboat, immerse yourself in our American roots from the Civil War to the Civil Rights Movement. Cruising the legendary Mississippi River, surround yourself with the landscapes and idyllic towns that inspired Mark Twain.

In Henderson, visit the Audubon Museum, which features many original works and join our expert guide to learn about the sense of natural wonder that this artist instilled in so many Americans. While in Louisville, take a behind the scenes tour of the Churchill Downs, the site of the famed Kentucky Derby, and explore the National Quilt Museum in Paducah, the world's largest museum devoted to quilt and fiber art.

At the end of an active day, return to the ship for relaxation and camaraderie as you sit down to a delicious meal and delightful conversation in our elegant restaurant.
Travel dates
- - Departing
  - From
  - Price From
- - Departing:12 Jul 24
  - From:Pittsburgh, Pennsylvania, USA
  - Price from: Ask
  - Details
- - Departing:4 Jul 25
  - From:Pittsburgh, Pennsylvania, USA
  - Price from: Ask
- - Departing:15 Aug 25
  - From:Pittsburgh, Pennsylvania, USA
  - Price from: Ask
  - Details

*Terms and Conditions

Information on this website has been obtained from the various Cruise Companies represented, however as the cruise industry is constantly changing and this information should be used as a guide only. We are unable to take responsibility for incorrect information and you must confirm all details the time of booking. Offer subject to availability at time of booking. Prices are per person share twin based on best available cruise fare, inclusive of all discounts unless otherwise stated. Where suite pricing is indicated this will be for lead in suite accommodation only and may in some cases be for a mini suite, which is the lead in suite category. Please ask for clarification at time of enquiry. Prices are subject to currency fluctuations and are based on cash or cheque. Cruise deposit, amendment and cancellation conditions apply. Travel agent service fees may apply. Special conditions apply - please ask for full details at time of enquiry.